Zi-Fan Yu, Sc.D. Senior Biostatistician

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Harmatz P, Giugliani R, Schwartz I, Guffon N, Teles EL, Sa Miranda MC, Wraith JE, Beck M, Arash L, Scarpa M, Yu Z, Wittes J, Berger K, Newman M, Lowe A, Kakkis E, Swiedler S. Enzyme replacement therapy for Mucopolysaccharidosis VI: a phase 3, randomized, double-blind, placebo-controlled, multinational study of recombinant human n-acetylgalactosamine 4-sulfatase (recombinant human arylsufatase B or rhASB) and follow-on, open-label extension study. Journal of Pediatrics, 2006; 148:533-539.

Yu Z, Catalano P, "Quantitative risk assessment for multivariate continuous outcomes with application to neurotoxicology: the bivariate case. Biometrics, 2005; 61:757-766.

Harmatz P, Ketteridege D, Giugliani R, Guffon N, Teles EL, Sa Miranda MC, Oates S, Yu Z, Sweidler SJ, Hopwood JJ. Direct comparison of measures of endurance, Mobility, and Joint Function During Enzyme Replacement Therapy of Mucopolysaccharidosis VI (Maroteaux-Lamy Syndrome): Results After 48 Weeks in a Phase 2 Open-Label Clinical Study of Recombinant Human N-acetylgalactosamine 4-sulfatase. Pediatrics, 2005; 115:681-689.

Radjev L, Yu Z, Wadler S, Weller E, Kahn S, Tormey D, Skeel R, Wiernick P. N-Methylformamide in advanced squamous cancer of the uterine cervix: an Eastern Cooperative Oncology Group phase II trial. Invest New Drugs 2001; 19:233-237.